dynamin inhibitory peptide Search Results


92
MedChemExpress hy p1083
Hy P1083, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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DynaMin inhibitory peptide, myristoylated (Cat No.: P000104), is a cell-permeable peptide inhibitor designed to block dynamin-dependent endocytosis. The myristoyl modification enhances membrane association and cellular uptake, enabling effective intracellular activity. By interfering with dynamin GTPase
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94
MedChemExpress dynamin inhibitory peptide
A , Timeline of the experiments. B , Representative confocal maximum projection images of dendritic sections of mature hippocampal neurons expressing scrambled (shNT) or KCC2a-specific (shKCC2a) shRNA, treated with a <t>dynamin</t> <t>inhibitory</t> peptide (DiP, 50 µM) 40 minutes before and during live Flag immunostaining. Scale: 5 µm. C , Summary boxplot showing the ratio of plasmalemmal (surf.) to the overall (total) KCC2b-Flag immunofluorescence intensity, normalized to control shNT condition. shNT control, n = 37; shNT +DiP, n = 39; shKCC2a control, n = 42; shKCC2a +DiP, n = 41 cells, from 4 independent cultures. Mann-Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. *p < 0.05. D , Representative confocal maximum projection images of dendritic sections of hippocampal neurons expressing scrambled (shNT) or KCC2a-specific shRNA. Two hours before immunostaining with a panKCC2 antibody, neurons were treated with either a proteasome blocker (MG132, 2.5 µM), an inhibitor of the ubiquitin-activating enzyme (PYR-41, 50 µM), or untreated (control). Scale: 5 µm. E , Summary boxplot showing the intensity of endogenous KCC2 immunofluorescence in the different conditions, normalized to shNT control. shNT control, n = 44; shNT +MG132, n = 38; shNT +PYR41, n = 43; shKCC2a control, n = 43; shKCC2a +MG132, n = 40; shKCC2a +PYR41, n = 44 cells, from 4 independent cultures. Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. **p < 0.01.
Dynamin Inhibitory Peptide, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dynamin+inhibitory+peptide/DynaMin+inhibitory+peptide%2C+myristoylated/bio_rxiv__64898__2026__01__25__701648-189-12-19
Average 94 stars, based on 1 article reviews
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GenScript corporation dynamin inhibitory control peptide, sequence prapnsrqpv
A , Timeline of the experiments. B , Representative confocal maximum projection images of dendritic sections of mature hippocampal neurons expressing scrambled (shNT) or KCC2a-specific (shKCC2a) shRNA, treated with a <t>dynamin</t> <t>inhibitory</t> peptide (DiP, 50 µM) 40 minutes before and during live Flag immunostaining. Scale: 5 µm. C , Summary boxplot showing the ratio of plasmalemmal (surf.) to the overall (total) KCC2b-Flag immunofluorescence intensity, normalized to control shNT condition. shNT control, n = 37; shNT +DiP, n = 39; shKCC2a control, n = 42; shKCC2a +DiP, n = 41 cells, from 4 independent cultures. Mann-Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. *p < 0.05. D , Representative confocal maximum projection images of dendritic sections of hippocampal neurons expressing scrambled (shNT) or KCC2a-specific shRNA. Two hours before immunostaining with a panKCC2 antibody, neurons were treated with either a proteasome blocker (MG132, 2.5 µM), an inhibitor of the ubiquitin-activating enzyme (PYR-41, 50 µM), or untreated (control). Scale: 5 µm. E , Summary boxplot showing the intensity of endogenous KCC2 immunofluorescence in the different conditions, normalized to shNT control. shNT control, n = 44; shNT +MG132, n = 38; shNT +PYR41, n = 43; shKCC2a control, n = 43; shKCC2a +MG132, n = 40; shKCC2a +PYR41, n = 44 cells, from 4 independent cultures. Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. **p < 0.01.
Dynamin Inhibitory Control Peptide, Sequence Prapnsrqpv, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dynamin+inhibitory+peptide/dynamin+inhibitory+control+peptide++sequence+prapnsrqpv/pm37730989-500-21-25
Average 90 stars, based on 1 article reviews
dynamin inhibitory control peptide, sequence prapnsrqpv - by Bioz Stars, 2026-10
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ChinaPeptides dynamin inhibitory peptide tat-qvpsrpnrap
A , Timeline of the experiments. B , Representative confocal maximum projection images of dendritic sections of mature hippocampal neurons expressing scrambled (shNT) or KCC2a-specific (shKCC2a) shRNA, treated with a <t>dynamin</t> <t>inhibitory</t> peptide (DiP, 50 µM) 40 minutes before and during live Flag immunostaining. Scale: 5 µm. C , Summary boxplot showing the ratio of plasmalemmal (surf.) to the overall (total) KCC2b-Flag immunofluorescence intensity, normalized to control shNT condition. shNT control, n = 37; shNT +DiP, n = 39; shKCC2a control, n = 42; shKCC2a +DiP, n = 41 cells, from 4 independent cultures. Mann-Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. *p < 0.05. D , Representative confocal maximum projection images of dendritic sections of hippocampal neurons expressing scrambled (shNT) or KCC2a-specific shRNA. Two hours before immunostaining with a panKCC2 antibody, neurons were treated with either a proteasome blocker (MG132, 2.5 µM), an inhibitor of the ubiquitin-activating enzyme (PYR-41, 50 µM), or untreated (control). Scale: 5 µm. E , Summary boxplot showing the intensity of endogenous KCC2 immunofluorescence in the different conditions, normalized to shNT control. shNT control, n = 44; shNT +MG132, n = 38; shNT +PYR41, n = 43; shKCC2a control, n = 43; shKCC2a +MG132, n = 40; shKCC2a +PYR41, n = 44 cells, from 4 independent cultures. Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. **p < 0.01.
Dynamin Inhibitory Peptide Tat Qvpsrpnrap, supplied by ChinaPeptides, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dynamin+inhibitory+peptide/dynamin+inhibitory+peptide+tat+qvpsrpnrap/pmc04223322-94-28-37
Average 90 stars, based on 1 article reviews
dynamin inhibitory peptide tat-qvpsrpnrap - by Bioz Stars, 2026-10
90/100 stars
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An inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis.
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Image Search Results


A , Timeline of the experiments. B , Representative confocal maximum projection images of dendritic sections of mature hippocampal neurons expressing scrambled (shNT) or KCC2a-specific (shKCC2a) shRNA, treated with a dynamin inhibitory peptide (DiP, 50 µM) 40 minutes before and during live Flag immunostaining. Scale: 5 µm. C , Summary boxplot showing the ratio of plasmalemmal (surf.) to the overall (total) KCC2b-Flag immunofluorescence intensity, normalized to control shNT condition. shNT control, n = 37; shNT +DiP, n = 39; shKCC2a control, n = 42; shKCC2a +DiP, n = 41 cells, from 4 independent cultures. Mann-Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. *p < 0.05. D , Representative confocal maximum projection images of dendritic sections of hippocampal neurons expressing scrambled (shNT) or KCC2a-specific shRNA. Two hours before immunostaining with a panKCC2 antibody, neurons were treated with either a proteasome blocker (MG132, 2.5 µM), an inhibitor of the ubiquitin-activating enzyme (PYR-41, 50 µM), or untreated (control). Scale: 5 µm. E , Summary boxplot showing the intensity of endogenous KCC2 immunofluorescence in the different conditions, normalized to shNT control. shNT control, n = 44; shNT +MG132, n = 38; shNT +PYR41, n = 43; shKCC2a control, n = 43; shKCC2a +MG132, n = 40; shKCC2a +PYR41, n = 44 cells, from 4 independent cultures. Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. **p < 0.01.

Journal: bioRxiv

Article Title: Differential isoform-specific control of KCC2 function in developing cortical neurons

doi: 10.64898/2026.01.25.701648

Figure Lengend Snippet: A , Timeline of the experiments. B , Representative confocal maximum projection images of dendritic sections of mature hippocampal neurons expressing scrambled (shNT) or KCC2a-specific (shKCC2a) shRNA, treated with a dynamin inhibitory peptide (DiP, 50 µM) 40 minutes before and during live Flag immunostaining. Scale: 5 µm. C , Summary boxplot showing the ratio of plasmalemmal (surf.) to the overall (total) KCC2b-Flag immunofluorescence intensity, normalized to control shNT condition. shNT control, n = 37; shNT +DiP, n = 39; shKCC2a control, n = 42; shKCC2a +DiP, n = 41 cells, from 4 independent cultures. Mann-Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. *p < 0.05. D , Representative confocal maximum projection images of dendritic sections of hippocampal neurons expressing scrambled (shNT) or KCC2a-specific shRNA. Two hours before immunostaining with a panKCC2 antibody, neurons were treated with either a proteasome blocker (MG132, 2.5 µM), an inhibitor of the ubiquitin-activating enzyme (PYR-41, 50 µM), or untreated (control). Scale: 5 µm. E , Summary boxplot showing the intensity of endogenous KCC2 immunofluorescence in the different conditions, normalized to shNT control. shNT control, n = 44; shNT +MG132, n = 38; shNT +PYR41, n = 43; shKCC2a control, n = 43; shKCC2a +MG132, n = 40; shKCC2a +PYR41, n = 44 cells, from 4 independent cultures. Whitney rank-sum tests, p-value corrected for multiple comparisons using the Holm-Šídák method. **p < 0.01.

Article Snippet: Clathrin-mediated endocytosis was inhibited by incubating neurons for 40 min with the Dynamin Inhibitory Peptide, myristoylated (DiP) (50 μM, MedChemExpress) in complete culture medium at 37°C.

Techniques: Expressing, shRNA, Immunostaining, Immunofluorescence, Control, MANN-WHITNEY, Ubiquitin Proteomics